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Poser criteria are diagnostic criteria for multiple sclerosis (MS). They replaced the older Schumacher criteria, and now they are considered obsolete as McDonald criteria have superseded them. Nevertheless, some of the concepts introduced have remained in MS research, like CDMS (clinical definite MS), and newer criteria are often calibrated against them.〔Christopher J. Lisanti, Patrick Asbach, and William G. Bradley, Jr. The Ependymal “Dot-Dash” Sign: An MR Imaging Finding of Early Multiple Sclerosis, AJNR Am J Neuroradiol 26:2033–2036, September 2005〕 The article that introduced them also defined the concepts of attack, historical information, clinical evidence, paraclinical evidence, lesion typical of MS, remission, separate lesions and laboratory support, which are necessary to apply the criteria. The authors defined a set of rules that can yield five conclusions: CDMS, LSDMS, CPMS, LSPMS or noMS. Poser diagnosis of CDMS is known to have a sensitivity of 87% respect postmortem autopsy examination〔Izquierdo G, Hauw J-J, Lyon-Caen O, et al: Value of multiple sclerosis diagnostic criteria: 70 Autopsy-confirmed cases. Arch Neurol 1985;42:848-850.〕 ==Definitions== Poser et al. define several concepts. The most important for diagnosis are: * Attack: Occurrence of a symptom of neurological dysfunction for more than 24 hours * Clinical evidence: Neurological dysfunction demonstrable by neurological examination * Paraclinical evidence: Demonstration by any test of the existence of a non-clinical lesion in the CNS 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Poser criteria」の詳細全文を読む スポンサード リンク
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